NMN (Nicotinamide Mononucleotide) supplementation shows promising results in increasing blood NAD+ levels and enhancing physical performance in humans, with some studies demonstrating improvements in walking distance and aerobic capacity. However, more research is needed to fully understand its long-term effects and optimal dosage, especially in relation to anti-aging benefits.
Increased NAD+ Levels:
Studies have shown that NMN supplementation can significantly increase blood NAD+ levels, a molecule that declines with age and is crucial for cellular energy and DNA repair.
Improved Physical Performance:
Some research indicates that NMN may enhance physical performance, particularly in older adults, with improvements observed in walking distance and aerobic capacity.
Metabolic Health:
NMN has shown potential in improving metabolic health markers, such as insulin sensitivity and lipid profiles, in animal models and some human studies.
Safety and Tolerability:
Human trials have generally shown that NMN is well-tolerated and safe, with some studies demonstrating no significant side effects at doses up to 900 mg daily.
Optimized Dosage:
Research suggests that a daily dose of 600 mg NMN may be optimal for maximizing blood NAD+ levels and physical performance benefits, according to studies.
Limited Long-Term Data:
While NMN shows promise, long-term data on its efficacy and safety are still limited, and more research is needed to fully understand its potential benefits and risks, especially regarding anti-aging.
Regulation and Availability:
In some regions, like the European Union, NMN is classified as a novel food and requires further safety studies before being allowed for use as a supplement, as reported by Decode Age.
*Source : Google
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